Application
Western blot analysis of motilin expression in non-transfected (A) and human motilin transfected (B) MLN whole cell lysates.| Product Name | motilin Antibody (FL-115) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-115 representing full length motilin of human origin |
| Modification Notes | Motilin, also known as MLN, is a 115 amino acid secreted peptide that is a cleavage product of the promotilin precursor, a protein that is proteolytically processed to yield motilin and motilin-associated peptide (MAP). Existing in the cells of the small intestine, motilin plays an important role in the rhythmic contraction of duodenal and colonic smooth muscle and is also involved in the regulation of interdigestive gastrointestinal motility. The gene encoding motilin maps to human chromosome 6, which contains 170 million base pairs and comprises nearly 6% of the human genome. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Additionally, Porphyria cutanea tarda, Parkinson's disease, Stickler syndrome and a susceptibility to bipolar disorder are all associated with genes that map to chromosome 6. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of motilin of human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-115 representing full length motilin of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-115 representing full length motilin of human origin |
| Entrez Gene | 4295 |
|---|
Application
Western blot analysis of motilin expression in non-transfected (A) and human motilin transfected (B) MLN whole cell lysates.| Application Notes | recommended for detection of motilin of human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
