Application
Immunofluorescence staining of formalin-fixed Hep G2 cells showing membrane localization.Application
Western blot analysis of TASK-2 expression in non-transfected: (A) and mouse TASK-2 transfected: (B) 293T whole cell lysates.Application
Western blot analysis of TASK-2 expression in Hep G2 whole cell lysate.| Product Name | TASK-2 Antibody (H-170) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 330-499 mapping at the C-terminus of TASK-2 of human origin |
| Modification Notes | K+ channels are divided into three subclasses, reflecting the number of transmembrane segments (TMS), which are designated 6TMS, 4TMS, and 2TMS. Members of the 4TMS class contain two distinct pore regions, and include TWIK, TREK, TRAAK, and TASK. TASK channels are highly sensitive to external pH in the physiological range. TASK-1 is expressed in brain and in rat heart, with high levels of expression in the right atrium. TASK-2, mainly expressed in kidney, is localized in cortical distal tubules and collecting ducts, suggesting a role in renal K+ transport. TASK-3 from rat cerebellum shares 54% identity with TASK-1, but less than 30% with TASK-2 and other tandem pore K+ channels. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of TASK-2 of mouse, rat and human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 330-499 mapping at the C-terminus of TASK-2 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 330-499 mapping at the C-terminus of TASK-2 of human origin |
| Entrez Gene | 8645 |
|---|
Application
Immunofluorescence staining of formalin-fixed Hep G2 cells showing membrane localization.
Application
Western blot analysis of TASK-2 expression in non-transfected: (A) and mouse TASK-2 transfected: (B) 293T whole cell lysates.
Application
Western blot analysis of TASK-2 expression in Hep G2 whole cell lysate.| Application Notes | recommended for detection of TASK-2 of mouse, rat and human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
