| Product Name | TNIK Antibody (S-16) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an internal region of TNIK of human origin |
| Modification Notes | The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/threonine (Ser/Thr) protein kinases. TNIK (TRAF2 and NCK-interacting protein kinase) is a 1,360 amino acid protein that contains one protein kinase domain and belongs to a subfamily of Ser/Thr protein kinases. Expressed ubiquitously with highest expression in brain, heart and skeletal muscle, TNIK functions as a stress-activated Ser/Thr kinase that catalyzes the ATP-dependent phosphorylation of target proteins and is thought to play a role in the response to environmental stress. Additionally, via its catalytic activity, TNIK may participate in cytoskeletal regulation events throughout the cell. TNIK exists as 8 isoforms that are produced by alternative splicing events. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of TNIK of mouse, rat and human origin by WB, IF and ELISA also reactive with additional species, including equine, canine, bovine and avian: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of TNIK of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of TNIK of human origin |
| Entrez Gene | 23043 |
|---|
| Application Notes | recommended for detection of TNIK of mouse, rat and human origin by WB, IF and ELISA also reactive with additional species, including equine, canine, bovine and avian: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
