recommended for detection of RBM42 of mouse, rat and human origin by WB, IP and ELISA
Modification Notes
Proteins containing RNA recognition motifs, including various hnRNP proteins, are implicated in the regulation of alternative splicing and protein components of snRNPs. The RBM (RNA-binding motif) gene family encodes proteins with an RNA binding motif that have been suggested to play a role in the modulation of apoptosis. RBM42 (RNA binding motif protein 42) is a 480 amino acid nuclear and cytoplasmic protein that belongs to the RRM RBM42 family and exists as four alternatively spliced isoforms. Identified as an hnRNP K binding protein, RBM42 contains one RRM (RNA recognition motif) domain through which it binds the 3'-untranslated region (UTR) of p21 mRNA. RBM42 may assist in the maintenance of cellular ATP levels during stress, most likely by protecting essential mRNAs, and is encoded by a gene that maps to human chromosome 19.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPELISA
WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
recommended for detection of RBM42 of mouse rat and human origin by WB IP and ELISA
Tissue Specificity
recommended for detection of RBM42 of mouse, rat and human origin by WB, IP and ELISA