Application
Western blot analysis of TIPIN expression in Jurkat whole cell lysate.| Product Name | TIPIN Antibody (Z-25) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | recommended for detection of TIPIN of mouse and human origin by WB, IP and ELISA |
| Modification Notes | TIPIN (Timeless interacting protein) is a 301 amino acid protein that localizes to both the nucleus and the cytoplasm and belongs to the CSM3 family. Expressed abundantly in liver, thymus, brain and gastrointestinal tract, TIPIN interacts with Timeless and is required for both normal cell cycle progression and for cell survival after DNA damage or replication stress. Additionally, TIPIN may be required to pass the ATR replication checkpoint that is induced by UV light or Hydroxyurea. Human TIPIN shares 72% amino acid identity with its mouse counterpart, suggesting a conserved role between species. The gene encoding TIPIN maps to human chromosome 15, which houses over 700 genes and comprises nearly 3% of the human genome. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPELISA |
| WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | recommended for detection of TIPIN of mouse and human origin by WB IP and ELISA |
|---|---|
| Tissue Specificity | recommended for detection of TIPIN of mouse and human origin by WB, IP and ELISA |
| Entrez Gene | 54962 |
|---|
Application
Western blot analysis of TIPIN expression in Jurkat whole cell lysate.| Application Notes | WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
