Application
Western blot analysis of SP140L expression in Jurkat whole cell lysate.| Product Name | SP140L Antibody (W-21) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | raised against synthetic SP140L peptide of human origin |
| Modification Notes | SP140L (nuclear body protein SP140-like protein) is a 438 amino acid protein that has significant sequence similarities to SP140, a component of the nuclear body that may be involved in trafficking between the nucleus and the cytoplasm. Expressed as three isoforms produced by alternative splicing, SP140L contains one HSR domain, one PHD-type zinc finger and one SAND domain. The gene that encodes SP140L maps to human chromosome 2, which consists of 237 million bases encoding over 1,400 genes and making up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alström syndrome is due to mutations in the ALMS1 gene. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPELISA |
| recommended for detection of SP140L of human origin by WB, IP and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | raised against synthetic SP140L peptide of human origin |
|---|---|
| Tissue Specificity | raised against synthetic SP140L peptide of human origin |
| Entrez Gene | 93349 |
|---|
Application
Western blot analysis of SP140L expression in Jurkat whole cell lysate.| Application Notes | recommended for detection of SP140L of human origin by WB, IP and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
