| Modification Notes |
LOC728169 is a 210 amino acid protein that is encoded by a gene which maps to human chromosome Y. Chromosome Y contains approximately 58 million base pairs and houses over 80 genes, many of which are essential for proper sexual development. The Y chromosome is the human sex determining chromosome which is necessary for male development and, while deletions or defects in chromosome Y-encoded genes are not lethal, they may greatly impair masculine development and function. Carrying an additional copy of the Y chromosome, as seen in males with XYY Syndrome, does not lead to an obvious phenotype and most XYY males are unaware of their additional Y chromosome. The LOC728169 gene product has been provisionally designated LOC728169 pending further characterization. |