Application
Western blot analysis of ZNF652 expression in HeLa whole cell lysate.| Product Name | ZNF652 Antibody (O-23) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | raised against ZNF652 of human origin |
| Modification Notes | Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. Zinc finger protein 652 (ZNF652) is a 606 amino acid member of the Krüppel C2H2-type zinc-finger protein family. Localized to the nucleus and highly expressed in breast, prostate and pancreas, ZNF652 contains nine C2H2-type zinc fingers, which are predicted to bind DNA. ZNF652 has been shown to interact with ETO-2, a putative breast tumor suppressor that represses transcription through its interaction with different DNA-binding zinc finger proteins. In this interaction, ZNF652 represses ETO-2 transcription, thereby playing a role in tumorigenesis. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBELISA |
| recommended for detection of ZNF652 of human origin by WB and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | raised against ZNF652 of human origin |
|---|---|
| Tissue Specificity | raised against ZNF652 of human origin |
| Entrez Gene | 22834 |
|---|
Application
Western blot analysis of ZNF652 expression in HeLa whole cell lysate.| Application Notes | recommended for detection of ZNF652 of human origin by WB and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
