| Product Name | Snf2 Antibody (y-300) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1404-1703 mapping at the C-terminus of Snf2 of Saccharomyces cerevisiae origin |
| Modification Notes | Maximal expression of G1 cyclins is induced by the heterodimeric transcription factor complex, which is composed of the DNA-binding subunit, Swi4 (also designated Art1), and Swi6 (1-3). In addition to binding Swi4, Swi6 forms a complex with Mbp1 that activates S-phase cyclins and genes involved in DNA synthesis (4). Rpb1 is the largest subunit of the yeast RNA polymerase II (5). Srb4 is a basal transcription factor that is essential for the establishment of the transcription initiation apparatus (5). Ssn6, a tandem tetratricopeptide repeat-containing protein, associates with Tup1 to form a general transcriptional repression complex (6). The yeast SNF-SWI complex is required for transcriptional activation of diverse genes and has been shown to alter chromatin structure (7). This complex has at least 10 components, including Snf2 (alternatively designated Swi2, Ric1, or Gam1), Snf5, Snf6, Swi1 (alternatively designated Adr6 or Gam3), and Swi3, and has been widely conserved (7). Transcriptional activators, Snf2 and Snf5, function by antagonizing repression mediated by nucleosomes (8). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Snf2 of Saccharomyces cerevisiae origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1404-1703 mapping at the C-terminus of Snf2 of Saccharomyces cerevisiae origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1404-1703 mapping at the C-terminus of Snf2 of Saccharomyces cerevisiae origin |
| Application Notes | recommended for detection of Snf2 of Saccharomyces cerevisiae origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
