Application
Western blot analysis of SLC25A46 expression in Jurkat whole cell lysate.| Product Name | SLC25A46 Antibody (O-22) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | raised against SLC25A46 of human origin |
| Modification Notes | SLC25A46 (solute carrier family 25 member 46) is a 418 amino acid multi-pass membrane protein that belongs to the the SLC25 family of mitochondrial carriers that are responsible for transporting metabolites across the inner mitochondrial membrane. Expressed in a variety of tissues, SLC25A46 contains two Solcar repeats and localizes to the mitochondrion inner membrane. The human gene encoding SLC25A46 localizes to chromosome 5. With 181 million base pairs encoding around 1,000 genes, chromosome 5 is about 6% of human genomic DNA. Chromosome 5 is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5 associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome. Deletion of 5q or chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPELISA |
| recommended for detection of SLC25A46 of mouse, rat, human, and zebra fish origin by WB, IP and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | raised against SLC25A46 of human origin |
|---|---|
| Tissue Specificity | raised against SLC25A46 of human origin |
| Entrez Gene | 91137 |
|---|
Application
Western blot analysis of SLC25A46 expression in Jurkat whole cell lysate.| Application Notes | recommended for detection of SLC25A46 of mouse, rat, human, and zebra fish origin by WB, IP and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
