Application
Western blot analysis of CNPase expression in non-transfected: (A) and human CNPase transfected: (B) 293T whole cell lysates.Application
Western blot analysis of CNPase expression in non-transfected: (A) and mouse CNPase transfected: (B) 293T whole cell lysates and mouse brain tissue extract (C).Application
Western blot analysis of CNPase expression in non-transfected: (A) and mouse CNPase transfected: (B) 293T whole cell lysates.Application
Western blot analysis of CNPase expression in non-transfected: (A) and human CNPase transfected: (B) 293T whole cell lysates.Application
Western blot analysis of CNPase expression in mouse (A) and rat (B) brain tissue extracts.| Product Name | CNPase Antibody (M-300) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 121-420 mapping at the C-terminus of CNPase of mouse origin |
| Modification Notes | 2',3'-cyclic nucleotide-3'-phosphodiesterase (CNPase) is a membrane-bound enzyme that can link tubulin to membranes and may regulate cytoplasmic microtubule distribution. CNPase acts as a microtubule-associated protein by promoting microtubule assembly; this activity resides in the C-terminus of the enzyme. CNPase is firmly associated with tubulin from brain tissue and thyroid cells and can be found at high concentrations in central nervous system myelin and in the outer segments of photoreceptors in the retina. Acute lead intoxication leads to disturbances in CNPase activity and the morphology of myelin. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of CNPase isoforms 1and 2 of mouse, rat and human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 121-420 mapping at the C-terminus of CNPase of mouse origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 121-420 mapping at the C-terminus of CNPase of mouse origin |
| Entrez Gene | 1267 |
|---|
Application
Western blot analysis of CNPase expression in non-transfected: (A) and human CNPase transfected: (B) 293T whole cell lysates.
Application
Western blot analysis of CNPase expression in non-transfected: (A) and mouse CNPase transfected: (B) 293T whole cell lysates and mouse brain tissue extract (C).
Application
Western blot analysis of CNPase expression in non-transfected: (A) and mouse CNPase transfected: (B) 293T whole cell lysates.
Application
Western blot analysis of CNPase expression in non-transfected: (A) and human CNPase transfected: (B) 293T whole cell lysates.
Application
Western blot analysis of CNPase expression in mouse (A) and rat (B) brain tissue extracts.| Application Notes | recommended for detection of CNPase isoforms 1and 2 of mouse, rat and human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
