Application
Western blot analysis of ZNF266 expression in Hep G2 whole cell lysate.Application
Immuno-peroxidase staining of formalin fixed, paraffin-embedded human cerebellum tissue showing nuclear and cytoplasmic staining.| Product Name | ZNF266 Antibody (E-24) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | raised against ZNF266 of human origin |
| Modification Notes | Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZNF266 is a 549 amino acid nuclear protein belonging to the Krüppel C2H2-type zinc finger protein family. ZNF266 has one KRAB domain and fourteen C2H2 zinc fingers. Due to the presence of these domains, ZNF266 is thought to be involved in transcriptional regulation. Repression of ZNF266 results in the blocking of erythroid differentiation and partial blocking of megakaryocytic differentiation, possibly indicating a role in the differentiation of erythroids and megakaryocytes. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFIHCELISA |
| recommended for detection of ZNF266 of human origin by WB, IP, IF, IHC(P) and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | raised against ZNF266 of human origin |
|---|---|
| Tissue Specificity | raised against ZNF266 of human origin |
| Entrez Gene | 10781 |
|---|
Application
Western blot analysis of ZNF266 expression in Hep G2 whole cell lysate.
Application
Immuno-peroxidase staining of formalin fixed, paraffin-embedded human cerebellum tissue showing nuclear and cytoplasmic staining.| Application Notes | recommended for detection of ZNF266 of human origin by WB, IP, IF, IHC(P) and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
