Application
Western blot analysis of SLC25A45 expression in Hep G2 whole cell lysate.Application
Immuno-peroxidase staining of formalin fixed, paraffin-embedded human kidney tissue showing cytoplasmic and nuclear staining.| Product Name | SLC25A45 Antibody (R-24) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | raised against SLC25A45 of human origin |
| Modification Notes | SLC25A45 (solute carrier family 25 member 45) is a 288 amino acid multi-pass membrane protein that belongs to the the SLC25 family of mitochondrial carriers that are responsible for transporting metabolites across the inner mitochondrial membrane. Expressed in a variety of tissues, SLC25A45 contains three Solcar repeats and localizes to the mitochondrion inner membrane. Due to alternative splicing events, four known isoforms exist for SLC25A45. The human gene encoding SLC25A45 localizes to chromosome 11. With approximately 135 million base pairs and 1,400 genes, chromosome 11 makes up around 4% of human genomic DNA and is considered a gene and disease association dense chromosome. Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene located on chromosome 11. Other disorders associated with defects in chromosome 11 include Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFIHCELISA |
| recommended for detection of SLC25A45 of human origin by WB, IP, IF, IHC(P) and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | raised against SLC25A45 of human origin |
|---|---|
| Tissue Specificity | raised against SLC25A45 of human origin |
| Entrez Gene | 283130 |
|---|
Application
Western blot analysis of SLC25A45 expression in Hep G2 whole cell lysate.
Application
Immuno-peroxidase staining of formalin fixed, paraffin-embedded human kidney tissue showing cytoplasmic and nuclear staining.| Application Notes | recommended for detection of SLC25A45 of human origin by WB, IP, IF, IHC(P) and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
