| Product Name | NY-ESO-1 Antibody (H-180) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 71-180 mapping at the C-terminus of NY-ESO-1 of human origin |
| Modification Notes | NY-ESO-1 (also known as autoimmunogenic cancer/testis antigen) is a tumor-specific shared antigen with distinctive immunogenicity. NY-ESO-1 is a member of the cancer/testis (CT) family of human tumor-associated antigens. NY-ESO-1 is an attractive candidate tumor antigen for the development of immunotherapy for a wide variety of cancers. NY-ESO-1 is expressed in multiple types of tumors, but its normal tissue distribution is primarily limited to the testis and ovaries. In addition, NY-ESO-1 elicits frequent antibody responses in cancer patients that are accompanied by strong CD8(+) T cell responses against HLA-A2-restricted epitopes. Therefore, both humoral and cellular immune responses can be mounted against NY-ESO-1. LAGE-1, also known as ESO-2, is observed in 25-50% of tumor samples of melanomas, non-small-cell lung carcinomas, bladder, prostate and head and neck cancers. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of NY-ESO-1 and 2 of human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 71-180 mapping at the C-terminus of NY-ESO-1 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 71-180 mapping at the C-terminus of NY-ESO-1 of human origin |
| Entrez Gene | 1485 |
|---|
| Application Notes | recommended for detection of NY-ESO-1 and 2 of human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
