| Product Name | RANTES Antibody (H-50) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 11-60 mapping near the N-terminus of T cell specific RANTES protein of human origin |
| Modification Notes | Structurally, C-C or b-chemokines are characterized by a set of conserved, adjacent cysteines. Members of this family include MCP-1, MCP-2, MCP-3, MIP-1å, MIP-1ß, RANTES and I-309. RANTES (regulated upon activation, normal T cell expressed and secreted) is expressed by platelets, eosinophils, fibroblasts, macrophages, endothelial cells and T lymphocytes. Consistent with its belonging to the chemokine family, RANTES exhibits strong chemoattractant activity towards monocytes and NK cells. I-309 was initially identified as a factor present in g/d T lymphocytes. I-309 cDNA encodes a protein 73 amino acids in length with one potential N-linked glycosylation site. Unlike the other members of the C-C family, I-309 does not induce chemotaxis in natural killer (NK) cells. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of RANTES of human and, to a lesser extent, mouse and rat origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 11-60 mapping near the N-terminus of T cell specific RANTES protein of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 11-60 mapping near the N-terminus of T cell specific RANTES protein of human origin |
| Entrez Gene | 6352 |
|---|
| Application Notes | recommended for detection of RANTES of human and, to a lesser extent, mouse and rat origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
