Application
Western blot analysis of TMEM86A expression in non-transfected: (A) and human TMEM86A transfected: (B) 293T whole cell lysates.| Product Name | TMEM86A Antibody (N-13) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping at the N-terminus of TMEM86A of human origin |
| Modification Notes | TMEM86A (transmembrane protein 86A) is a 220 amino acid protein encoded by a gene mapping to human chromosome 11. With approximately 135 million base pairs and 1,400 genes, chromosome 11 makes up around 4% of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and ∫ thalassemia are caused by HBB gene mutations. Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of TMEM86A of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with TMEM86B also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping at the N-terminus of TMEM86A of human origin |
|---|---|
| Tissue Specificity | epitope mapping at the N-terminus of TMEM86A of human origin |
| Entrez Gene | 144110 |
|---|
Application
Western blot analysis of TMEM86A expression in non-transfected: (A) and human TMEM86A transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of TMEM86A of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with TMEM86B also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
