Application
Western blot analysis of AQP6 expression in CCD-1064Sk whole cell lysate.| Product Name | AQP6 Antibody (H-45) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 238-282 mapping within a C-terminal cytoplasmic domain of AQP6 of human origin |
| Modification Notes | AQP6 (also designated AQP2L) is a 282 amino acid protein that localizes to intracellular membranes in renal epithelia. Aquaporins (AQPs) are a large family of integral membrane water transport channel proteins that facilitate the transport of water through the cell membrane. This function is conserved in animals, plants and bacteria. Many isoforms of aquaporin have been identified in mammals, designated AQP0 through AQP10. Aquaporins are widely distributed; it is not uncommon for more than one type of AQP to be present in the same cell. Although most aquaporins are permeable only to water, AQP3, AQP7, AQP9 and one of the two AQP10 transcripts are also permeable to urea and glycerol. Aquaporins are involved in renal water absorption, generation of pulmonary secretions, lacrimation and the secretion and reabsorption of cerebrospinal fluid and aqueous humor. AQP6 may contribute to glomerular filtration, tubular endocytosis and acid-base metabolism. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of AQP6 of human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 238-282 mapping within a C-terminal cytoplasmic domain of AQP6 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 238-282 mapping within a C-terminal cytoplasmic domain of AQP6 of human origin |
| Entrez Gene | 363 |
|---|
Application
Western blot analysis of AQP6 expression in CCD-1064Sk whole cell lysate.| Application Notes | recommended for detection of AQP6 of human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
