Application
Western blot analysis of PITSLRE expression in WI 38 whole cell lysate (A) and mouse thymus tissue extract (B).Application
Western blot analysis of PITSLRE expression in mouse thymus tissue extract.Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human adrenal gland tissue showing nuclear and cytoplasmic staining of cortical cells (low and high magni?fication). Kindly provided by The Swedish Human Protein Atlas (HPA) program.| Product Name | PITSLRE Antibody (C-17) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping at the C-terminus of PITSLRE A of human origin |
| Modification Notes | The PITSLRE ∫1 protein, a distantly related member of the Cdk family of protein kinases, induces apoptosis after low levels of ectopic expression. Apoptosis, or programmed cell death, is similarly induced by ectopic expression of an amino terminal deletion mutant retaining the catalytic and carboxy terminal domains of PITSLRE ∫1, but not by other mutants lacking histone H1 kinase activity or by other Cdk family members. The terminology for the ten isoforms of the PITSLRE subfamily of proteins is based on the conserved PSTAIRE box region of Cdc2 p34. Depending on which of the PITSLRE genes produce the protein, the cDNA and protein are designated å, ∫ or © (i.e., PITSLRE A gene, å; PITSLRE B gene, ∫ and PITSLRE C gene, ©). Some of the isoforms such as PITSLRE å1 (T cells) and PITSLRE ∫1 (B cells and brain), are expressed in specific cell types, while others are expressed ubiquitously. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFIHCELISA |
| recommended for detection of PITSLRE A and PITSLRE B of human origin and PITSLRE of mouse and rat origin by WB, IP, IF, IHC(P) and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping at the C-terminus of PITSLRE A of human origin |
|---|---|
| Tissue Specificity | epitope mapping at the C-terminus of PITSLRE A of human origin |
| Entrez Gene | 984 |
|---|
Application
Western blot analysis of PITSLRE expression in WI 38 whole cell lysate (A) and mouse thymus tissue extract (B).
Application
Western blot analysis of PITSLRE expression in mouse thymus tissue extract.
Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human adrenal gland tissue showing nuclear and cytoplasmic staining of cortical cells (low and high magni?fication). Kindly provided by The Swedish Human Protein Atlas (HPA) program.| Application Notes | recommended for detection of PITSLRE A and PITSLRE B of human origin and PITSLRE of mouse and rat origin by WB, IP, IF, IHC(P) and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
