Application
Western blot analysis of LENG4 expression in Jurkat whole cell lysate.| Product Name | LENG4 Antibody (Q-23) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | recommended for detection of LENG4 of human origin by WB, IP and ELISA |
| Modification Notes | The membrane-bound O-acyltransferase family is a group of integral membrane proteins with acyltransferase activity. LENG4 (membrane bound O-acyltransferase domain containing 7), also known as lysophospholipid acyltransferase 7, leukocyte receptor cluster member 4, MBOAT7, BB1, LPLAT 7, LRC4 or OACT7, is a 472 amino acid multi-pass membrane protein involved in lipid and phospholipid metabolism. LENG4 belongs to the membrane-bound acyltransferase family and participates in the Land cycle by catalyzing reacylation of phospholipids. LENG4 is responsible for the conversion of lysophosphatidylinositol into phosphatidylinositol, and prefers arachidonoyl-CoA as its acyl donor. Overexpressed in metastatic breast and bladder carcinomas, LENG4 is down-regulated by gamma-interferon. Three LENG4 isoforms exist due to alternative splicing events, and LENG4 is encoded by a gene mapping to human chromosome 19q13.42. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPELISA |
| WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | recommended for detection of LENG4 of human origin by WB IP and ELISA |
|---|---|
| Tissue Specificity | recommended for detection of LENG4 of human origin by WB, IP and ELISA |
| Entrez Gene | 79143 |
|---|
Application
Western blot analysis of LENG4 expression in Jurkat whole cell lysate.| Application Notes | WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
