Application
Western blot analysis of 6CKine expression in mouse thymus tissue extract.| Product Name | 6CKine Antibody (FL-134) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-134 representing full length 6CKine of human origin |
| Modification Notes | 6Ckine (also designated Exodus-2, SLC, or TCA4) is a member of the chemokine superfamily and the subfamily of CC chemokines that has an aspartate-cysteine-cysteine-leucine motif near its amino terminus (1). 6Ckine has a unique 36 or 37 (murine and human, respectively) amino acid carboxyl-terminal extension that containins six conserved cysteines (2,3). 6Ckine stimulates the chemotaxis of T-lymphocytes and the recruitment and proliferation of activated NK cells (1,2). Expression of human 6Ckine is restricted to lymph node, spleen, and appendix, while murine 6Ckine has a broader tissue distribution in spleen and lung (3). 6Ckine is involved in inhibiting hematopoiesis both in vitro and in vivo (4). The chemokine family is composed of structurally related proteins that mediate all leukocyte migration (4). Chemokines stimulate leukocyte infiltration and therefore play crucial roles in many diseases in which there is inflammatory tissue destruction (5-8). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of 6CKine of mouse, rat and human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-134 representing full length 6CKine of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-134 representing full length 6CKine of human origin |
| Entrez Gene | 6366 |
|---|
Application
Western blot analysis of 6CKine expression in mouse thymus tissue extract.| Application Notes | recommended for detection of 6CKine of mouse, rat and human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
