Application
Immunofluorescence staining of methanol-fixed HeLa cells showing membrane localization.Application
Western blot analysis of GABARAP expression in non-transfected: (A) and mouse GABARAP transfected: (B) 293T whole cell lysates.Application
Western blot analysis of GABARAP expression in non-transfected: (A) and mouse GABARAP transfected: (B) 293T whole cell lysates.Application
Western blot analysis of human recombinant GABARAP GST fustion protein.Application
Western blot analysis of human recombinant GABARAP fusion protein.| Product Name | GABARAP Antibody (FL-117) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-117 representing full length GABARAP of human origin |
| Modification Notes | In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl-conductance that inhibits neuronal firing (1). GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC (2,3). In addition to GABA receptors, several proteins have been identified as regulators of GABA function, including GAD65, GAD67, GABA transporters and GABARAP (GABAA receptor-associated protein) (4-6). GABARAP associates with GABAA Rg2 to link GABAA receptors to the cytoskeleton (6). The GABARAP protein sequence is similar to light chain-3 of microtubule-associated proteins (MAPs) suggesting that it may be a type of MAP or a component of a MAP complex (6). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of GABARAP and GABARAP like-2 protein of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-117 representing full length GABARAP of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-117 representing full length GABARAP of human origin |
| Entrez Gene | 11337 |
|---|
Application
Immunofluorescence staining of methanol-fixed HeLa cells showing membrane localization.
Application
Western blot analysis of GABARAP expression in non-transfected: (A) and mouse GABARAP transfected: (B) 293T whole cell lysates.
Application
Western blot analysis of GABARAP expression in non-transfected: (A) and mouse GABARAP transfected: (B) 293T whole cell lysates.
Application
Western blot analysis of human recombinant GABARAP GST fustion protein.
Application
Western blot analysis of human recombinant GABARAP fusion protein.| Application Notes | recommended for detection of GABARAP and GABARAP like-2 protein of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
