Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human skeletal muscle tissue showing cytoplasmic and nuclear staining of myocytes.Application
Western blot analysis of SSTR1 expression in MIA PaCa-2 whole cell lysate.Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human parathyroid gland tissue showing membrane and cytoplasmic staining of glandular cells at low (A) and high (B) magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.Application
Western blot analysis of SSTR1 expression in KNRK whole cell lysate.| Product Name | SSTR1 Antibody (H-60) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 21-70 of SSTR1 of human origin |
| Modification Notes | SSTRs (for somatostatin receptors) represent a family of G-protein-coupled receptors which mediate the diverse biological actions of somatostatin (SST) (1). There are five distinct subtypes of SSTRs that bind two natural ligands, SST-14 and SST-28 (1). SSTR2 gives rise to spliced variants, SSTR2A and 2B (1). SSTRs share common signaling pathways such as the ability to inhibit adenylyl cyclase via GTP binding proteins (1-3). Some of the subtypes are also coupled to tyrosine phosphatase (SSTR1,2), Ca2+ channels (SSTR2), Na+/H+ exchanger (SSTR1), PLA-2 (SSTR4), and MAP kinase (SSTR4) (1). Individual target cells typically express more than one SSTR subtype and often all five isoforms (4,5). Subtypes of SSTR can form functional homo- and heterodimers (6,7). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFIHCELISA |
| recommended for detection of SSTR1 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 21-70 of SSTR1 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 21-70 of SSTR1 of human origin |
| Entrez Gene | 6751 |
|---|
Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human skeletal muscle tissue showing cytoplasmic and nuclear staining of myocytes.
Application
Western blot analysis of SSTR1 expression in MIA PaCa-2 whole cell lysate.
Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human parathyroid gland tissue showing membrane and cytoplasmic staining of glandular cells at low (A) and high (B) magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.
Application
Western blot analysis of SSTR1 expression in KNRK whole cell lysate.| Application Notes | recommended for detection of SSTR1 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
