epitope corresponding to amino acids 131-280 mapping near the N-terminus of Thrombospondin 3 of human origin
Modification Notes
The Thrombospondin proteins (TSP 1-5) compose a family of glycoproteins that are involved in cell-to-cell and cell-to-matrix signaling. These extracellular, cell-surface proteins form complexes of both homo- and hetero-multimers. Thrombospondins play a role in development, aggregation of platelets, adhesion and migration of cells and progression of cells through the growth cycle. Thrombospondin 1 is released from platelets in response to Thrombin stimulation and is a transient component of the extracellular matrix of developing and repairing tissues. Thrombospondin 2 shares a high degree of homology with Thrombospondin 1, and is thought to have overlapping but unique functions. Thrombospondin 3 is a developmentally regulated heparin-binding protein. Thrombospondin 4 is neuronally expressed and stimulates neurite outgrowth.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of Thrombospondin 3 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope corresponding to amino acids 131-280 mapping near the N-terminus of Thrombospondin 3 of human origin
Tissue Specificity
epitope corresponding to amino acids 131-280 mapping near the N-terminus of Thrombospondin 3 of human origin
Western blot analysis of Thrombospondin 3 expression in mouse pituitary tissue extract.
Application Notes
recommended for detection of Thrombospondin 3 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine:
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.