Application
Western blot analysis of BRINP3 expression in rat pituitary tissue extract.| Product Name | BRINP3 Antibody (N-16) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping near the N-terminus of BRINP3 of human origin |
| Modification Notes | BRINP3, also known as DBCCR1L, DBCCR1L1 (DBCCR1-like protein 1) or FAM5C, is a 766 amino acid secreted protein that belongs to the FAM5 family and has been shown to contributes to aggressive periodontitis. A potential novel tumor suppressor gene in tongue squamous cell carcinoma, BRINP3 is encoded by a gene that maps to human chromosome 1q31.1. Chromosome 1 spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of BRINP3 of human origin and Fam5c of mouse and rat origin by WB, IP, IF and ELISA non cross-reactive with BRINP2 also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping near the N-terminus of BRINP3 of human origin |
|---|---|
| Tissue Specificity | epitope mapping near the N-terminus of BRINP3 of human origin |
| Entrez Gene | 339479 |
|---|
Application
Western blot analysis of BRINP3 expression in rat pituitary tissue extract.| Application Notes | recommended for detection of BRINP3 of human origin and Fam5c of mouse and rat origin by WB, IP, IF and ELISA non cross-reactive with BRINP2 also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
