| Product Name | ECOP Antibody (E-13) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an internal region of ECOP of human origin |
| Modification Notes | ECOP (EGFR-coamplified and overexpressed protein), also known as VOPP1 (vesicular, overexpressed in cancer, prosurvival protein 1) or GASP (glioblastoma-amplified secreted protein), is a 172 amino acid protein that is coamplified with EGFR and overexpressed in multiple glioblastomas. Highly expressed in ovary and thymus, ECOP is found at moderate levels in testis, colon, small intestine, and spleen, and at low levels in liver, placenta and prostate. ECOP regulates NF˚B signaling and may have a role in resistance to apoptosis. The gene encoding ECOP maps to human chromosome 7, which houses over 1,000 genes, comprises nearly 5% of the human genome and has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of ECOP and LOC729086 of mouse, rat and human origin by WB, IF and ELISA also reactive with additional species, including equine and bovine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of ECOP of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of ECOP of human origin |
| Entrez Gene | 81552 |
|---|
| Application Notes | recommended for detection of ECOP and LOC729086 of mouse, rat and human origin by WB, IF and ELISA also reactive with additional species, including equine and bovine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
