Application
Western blot analysis of RCL expression in non-transfected: (A) and mouse RCL transfected: (B) 293T whole cell lysates and HeLa (C), K-562 (D), Jurkat (E) and MCF7 (F) nuclear extracts.Application
Western blot analysis of RCL expression in Hep G2 whole cell lysate.| Product Name | RCL Antibody (FL-174) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-174 representing full length RCL of human origin |
| Modification Notes | RCL is a 174 amino acid protein that belongs to the deoxyribonucleoside 5'-monophosphate N-glycosidase family. It is suggested that the RCL protein plays a role during cellular proliferation and c-Myc-mediated transformation. RCL is expressed at high levels in heart, kidney, liver, skeletal muscle and spleen, low levels in brain, colon, lung, peripheral blood leukocytes, placenta, small intestine and thymus, and overexpressed in a significant proportion of breast cancers. Localizing to nucleus and cytoplasm, expression of RCL is induced by ER81. The RCL gene is conserved in chimpanzee, dog, mouse, rat and zebrafish, and maps to human chromosome 6p21.1. Making up nearly 6% of the human genome, chromosome 6 contains around 1,200 genes within 170 million base pairs of sequence. Notably, the PARK2 gene, which is associated with Parkinson's disease, and the genes encoding the major histocompatiblity complex proteins, which are key molecular components of the immune system and determine predisposition to rheumatic diseases, are also located on chromosome 6. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of RCL of mouse, rat and human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-174 representing full length RCL of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-174 representing full length RCL of human origin |
| Entrez Gene | 10591 |
|---|
Application
Western blot analysis of RCL expression in non-transfected: (A) and mouse RCL transfected: (B) 293T whole cell lysates and HeLa (C), K-562 (D), Jurkat (E) and MCF7 (F) nuclear extracts.
Application
Western blot analysis of RCL expression in Hep G2 whole cell lysate.| Application Notes | recommended for detection of RCL of mouse, rat and human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
