Application
Western blot analysis of human recombinant TGFα fusion protein.| Product Name | TGFα Antibody (H-50) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 40-89 representing mature TGFα of human origin |
| Modification Notes | Transforming growth factor-å (TGFå) is an acid- and heat-stable 50 amino acid protein originally found in rodents and humans. TGFå is 33% homologous at the amino acid level to epidermal growth factor (EGF). TGFå binds to the EGF receptor, mediates tyrosine phosphorylation of the receptor and promotes anchorage-independent growth of normal rat fibroblasts in soft agar in the presence of transforming growth factor-∫. TGFa is secreted by a variety of transformed cells and tumors, embryonic cells and some normal adult cells. TGFå bioactivity has been found in the urine of cancer patients. It has been suggested that it may act as an autocrine growth factor for the induction or maintenance of malignancy. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of TGFα of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 40-89 representing mature TGF&alpha of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 40-89 representing mature TGFα of human origin |
| Entrez Gene | 7039 |
|---|
Application
Western blot analysis of human recombinant TGFα fusion protein.| Application Notes | recommended for detection of TGFα of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
