Application
Western blot analysis of DDEFL1 expression in non-transfected: (A) and mouse DDEFL1 transfected: (B) 293T whole cell lysates.| Product Name | DDEFL1 Antibody (M-194) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 711-904 mapping at the C-terminus of DDEFL1 of mouse origin |
| Modification Notes | DDEFL1 (development and differentiation enhancing factor-like 1), also known as ACAP4, UPLC1, CENTB6 or ASAP3 (ArfGAP with SH3 domain, ankyrin repeat and PH domain 3), is a 903 amino acid cytoplasmic protein belonging to the subfamily of ADP-ribosylation factor (Arf) GTPase-activating proteins. DDEFL1 contains two ANK repeats, an Arf-GAP domain and a PH domain, and is expressed in lung, liver, blood leukocytes and primary hepatocarcinoma. The Arf-GAP domain of DDEFL1 catalyzes the hydrolysis of GTP bound to Arf proteins. DDEFL1 promotes cell differentiation and migration, and has been implicated in the pathogenesis of hepatocellular carcinoma. Existing as two isoforms produced by alternative splicing events, DDEFL1 is encoded by a gene located on human chromosome 1. Human chromosome 1 spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of DDEFL1 of mouse and rat origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 711-904 mapping at the C-terminus of DDEFL1 of mouse origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 711-904 mapping at the C-terminus of DDEFL1 of mouse origin |
| Entrez Gene | 230837 |
|---|
Application
Western blot analysis of DDEFL1 expression in non-transfected: (A) and mouse DDEFL1 transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of DDEFL1 of mouse and rat origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
