| Product Name | PPIH Antibody (H-38) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 140-177 mapping at the C-terminus of PPIH of human origin |
| Modification Notes | PPIH (peptidylprolyl isomerase H (cyclophilin H)), also known as PPIase H, Rotamase H, CypH, CYP20 or USA-CYP (U-snRNP-associated cyclophilin SnuCyp-20), is a 177 amino acid protein that belongs to the cyclophilin-type PPIase family. PPIH may accelerate the folding of proteins and catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. PPIH is thought to participate in pre-mRNA splicing with processing factors PRPF3, PRPF4, and PRPF18 and may be involved in the assembly of the U4/U5/U6 tri-snRNP complex. Considered a protein chaperone, PPIH possesses PPlase activity and mediates the interactions between different proteins inside the spliceosome. PPIH contains one PPIase cyclophilin-type domain and is inhibited by cyclosporin A. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of PPIH of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 140-177 mapping at the C-terminus of PPIH of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 140-177 mapping at the C-terminus of PPIH of human origin |
| Entrez Gene | 10465 |
|---|
| Application Notes | recommended for detection of PPIH of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
