| Product Name | PGD Antibody (D-17) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an internal region of PGD of human origin |
| Modification Notes | PGD (phosphogluconate dehydrogenase), also referred to as 6PGD, is a 483 amino acid enzyme that is involved in the pentose phosphate shunt. Pentose is required for nucleic acid biosynthesis and the pentose phosphate cycle is a major source of NADPH. As the second dehydrogenase in the pentose phosphate cycle, PGD catalyzes the oxidative decarboxylation of PGD to ribulose 5-phosphate, following the release of CO2 and the reduction of NADP. PGD deficiency increases the level of erythrocyte pyruvate kinase (PK) activity and reduces glutathione synthetase (GSH), resulting in hemolysis. Defects in PGD are generally asymptomatic and are inherited in an autosomal dominant fashion. Catalytic active regions of PGD, such as those forming the substrate and coenzyme binding sites, are highly conserved in most species. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of PGD of mouse, rat and human origin by WB, IF and ELISA also reactive with additional species, including bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of PGD of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of PGD of human origin |
| Entrez Gene | 5226 |
|---|
| Application Notes | recommended for detection of PGD of mouse, rat and human origin by WB, IF and ELISA also reactive with additional species, including bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
