Application
Western blot analysis of MOCS2 expression in non-transfected: (A) and human MOCS2 transfected: (B) 293T whole cell lysates.| Product Name | MOCS2 Antibody (FL-188) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-188 representing full length MOCS2 of human origin |
| Modification Notes | MOCS2 (molybdopterin synthase) is a heterotetrameric synthase composed of two small (MOCS2A) and two large (MOCS2B) subunits. The small and large subunits are both encoded by a single bicistronic mRNA, with the open reading frames overlapping by 77 nucleotides. MOCS2 functions in the second step of the synthesis of molybdenum cofactor or molybdopterin (MPT). It catalyzes the formation of MPT from precursor Z by incorporating a dithiolene functional group. The C-terminus of the small subunit of MOCS2 acts as the sulfur donor for the synthesis of this functional group. MPT is inserted into molybdoenzymes and is required for the proper function of aldehyde oxidase, xanthine dehydrogenase and sulphite oxidase enzymes. Mutations in the gene encoding MOCS2 can lead to molybdenum cofactor deficiency and can result in early childhood death. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of MOCS2 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-188 representing full length MOCS2 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-188 representing full length MOCS2 of human origin |
| Entrez Gene | 4338 |
|---|
Application
Western blot analysis of MOCS2 expression in non-transfected: (A) and human MOCS2 transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of MOCS2 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
