| Product Name | CLEC-6 Antibody (M-77) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 44-120 mapping within an extracellular domain of CLEC-6 of mouse origin |
| Modification Notes | The human ∫-glucan protein (Dectin-1) is a small, type II transmembrane receptor that enables ∫-glucan dependent, nonopsonic recognition of zymosan and other yeast-derived particles by primary macrophages. Dectin-1 is expressed in dendritic cells, and is the human homologue of the C-type (calcium dependent) lectin-like receptor (CLEC) family that plays an important role in regulating innate immunity. The CLEC protein structure has a specific fold that provides a highly static scaffold for combinatorial display of variable antigen residues. This fold differs from the classic immunoglobulin fold, illustrating an evolutionary solution for balancing diversity against stability. CLEC-6 is a single-pass, type II transmembrane protein that is highly expressed in bone marrow and spleen and weakly expressed in peripheral blood leukocytes. CLEC-6 may function as a receptor in the antigen uptake at the infection location. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of CLEC-6 of mouse and rat origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 44-120 mapping within an extracellular domain of CLEC-6 of mouse origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 44-120 mapping within an extracellular domain of CLEC-6 of mouse origin |
| Application Notes | recommended for detection of CLEC-6 of mouse and rat origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
