epitope corresponding to amino acids 21-242 mapping at the C-terminus of IL-34 of human origin
Modification Notes
The interleukins (ILs) are a broad family of well characterized cytokines, primarily of hematopoietic cell origin. They are secreted by immune cells (mainly macrophages, B-cells or T-cells) that regulate a wide range of immune system functions. The specific functions of different interleukins vary from the regulation of inflammatory and immune responses to the regulation of other interleukins. IL-34 (interleukin-34) is a 235 amino acid secreted mouse protein that belongs to the interleukin family of cytokines. Existing as a homodimer, IL-34 functions to promote the viability and differentiation of macrophages and monocytes and may also act as a ligand for c-Fms/CSF-1R, a colony-stimulating factor. Multiple alternatively spliced isoforms of IL-34 exist, all of which are encoded by a gene that maps to mouse chromosome 8.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of IL-34 of human and, to a lesser extent, mouse and rat origin by WB, IP, IF and ELISA:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope corresponding to amino acids 21-242 mapping at the C-terminus of IL-34 of human origin
Tissue Specificity
epitope corresponding to amino acids 21-242 mapping at the C-terminus of IL-34 of human origin
Application
Application
Western blot analysis of IL-34 expression in SK-N-MC whole cell lysate.
Application Notes
recommended for detection of IL-34 of human and, to a lesser extent, mouse and rat origin by WB, IP, IF and ELISA:
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.