Application
Immunofluorescence staining of formalin-fixed Hep G2 cells showing membrane localization.Application
Western blot analysis of ALG11 expression in HeLa (A), MDA-MB-468 (B), Jurkat (C) and Hep G2 (D) whole cell lysates.| Product Name | ALG11 Antibody (K-17) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an internal region of ALG11 of human origin |
| Modification Notes | ALG11 (asparagine-linked glycosylation 11), also known as GT8 or UTP14C, is a 492 amino acid multi-pass membrane proteins that is thought to play a role in spermatogenesis and is encoded by a gene which maps to chromosome 13. Comprising nearly 4% of the human genome, chromosome 13 contains around 114 million base pairs and encodes over 400 genes. Chromosome 13 houses key tumor suppressor genes, including BRCA2 and RB1, which are associated with breast cancer susceptibility and retinoblastoma, respectively. Trisomy 13, also known as Patau syndrome, is deadly and the few who survive past one year suffer from permanent neurologic defects, difficulty eating and vulnerability to serious respiratory infections. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of ALG11 of m and h origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of ALG11 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of ALG11 of human origin |
| Entrez Gene | 440138 |
|---|
Application
Immunofluorescence staining of formalin-fixed Hep G2 cells showing membrane localization.
Application
Western blot analysis of ALG11 expression in HeLa (A), MDA-MB-468 (B), Jurkat (C) and Hep G2 (D) whole cell lysates.| Application Notes | recommended for detection of ALG11 of m and h origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
