| Product Name | VG5Q Antibody (H-78) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-78 mapping at the N-terminus of VG5Q of human origin |
| Modification Notes | Angiogenic factors are critical to the initiation of angiogenesis and maintenance of the vascular network. The angiogenic factor vasculogenesis gene on 5q (VG5Q, formally named AGGF1) binds to endothelial cells and promotes cell proliferation and angiogenesis. Suppression of VG5Q inhibits vessel formation. VG5Q may also play a role in the autocrine system. It is a secreted cytoplasmic protein that interacts with TWEAK (also designated TNFSF12), an angiogenic factor. VG5Q is widely expressed, but highest levels are detected in various types of endothelial cells, osteoblasts and in smooth muscle cells. Mutations in the VG5Q gene result in the vascular disease Klippel-Trenaunay syndrome (KTS), which results in asymmetric overgrowth. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of VG5Q of mouse, rat and human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-78 mapping at the N-terminus of VG5Q of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-78 mapping at the N-terminus of VG5Q of human origin |
| Entrez Gene | 55109 |
|---|
| Application Notes | recommended for detection of VG5Q of mouse, rat and human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
