Application
Western blot analysis of TMEM70 expression in PC-3 (A), K-562 (B), MOLT-4 (C) and T-47D (D) whole cell lysates.| Product Name | TMEM70 Antibody (FL-260) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-260 representing full length TMEM70 of human origin |
| Modification Notes | TMEM70 (transmembrane protein 70) is a 260 amino acid multi-pass mitochondrial membrane protein that exists as multiple alternatively spliced isoforms which are expressed in pancreas, liver, muscle and kidney tissue. Mutations in the gene encoding TMEM70 are associated with ATP synthase deficiency and neonatal mitochondrial encephalocardiomyopathy, suggesting that TMEM70 plays an important role in ADP-stimulated respiration, mitochondrial ATP synthesis, ATP hydrolysis and the maintenance of membrane potential. The gene encoding TMEM70 maps to human chromosome 8, which consists of nearly 146 million base pairs, houses more than 800 genes and is associated with a variety of diseases and malignancies. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of TMEM70 of human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-260 representing full length TMEM70 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-260 representing full length TMEM70 of human origin |
| Entrez Gene | 54968 |
|---|
Application
Western blot analysis of TMEM70 expression in PC-3 (A), K-562 (B), MOLT-4 (C) and T-47D (D) whole cell lysates.| Application Notes | recommended for detection of TMEM70 of human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
