Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human small intestine tissue showing apical membrane and cytoplasmic staining of glandular cells and cytoplasmic staining of interstitial cells.Application
Western blot analysis of PCTAIRE-1 expression in non-transfected: (A) and mouse PCTAIRE-1 transfected: (B) 293T whole cell lysates.Application
Western blot analysis of PCTAIRE-1 expression in non-transfected: (A) and mouse PCTAIRE-1 transfected: (B) 293T whole cell lysates.Application
Western blot analysis of PCTAIRE-1 expression in U-87 MG (A), A549 (B) and MCF7 (C) whole cell lysates.| Product Name | PCTAIRE-1 Antibody (C-16) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping at the C-terminus of PCTAIRE-1 of human origin |
| Modification Notes | Cell cycle progression is controlled in part by a family of cyclin proteins and cyclin dependent kinases (Cdks). Cdk proteins work in concert with cyclins to phosphorylate key substrates involved in cell cycle progression. Another family of proteins, Cdk inhibitors, also play a role in regulating the cell cycle by binding to cyclin-Cdk complexes and modulating their activity. Members of the Cdk family include Cdk2-Cdk8, PCTAIRE-1-3, PITALRE and PITSLRE. PCTAIRE-1, PCTAIRE-2 and PCTAIRE-3 comprise a subfamily of cdc2-related serine/threonine kinases. PCTAIRE-1, which is expressed primarily in mammalian brain, interacts with a variety of proteins, and is thought to be part of a multiple signal transduction cascade. PCTAIRE-2, also with expression in brain, may be important in terminally differentiated neurons. The human PCTAIRE-3 gene maps to chromosome 1q31-q32. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFIHCELISA |
| recommended for detection of PCTAIRE-1 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping at the C-terminus of PCTAIRE-1 of human origin |
|---|---|
| Tissue Specificity | epitope mapping at the C-terminus of PCTAIRE-1 of human origin |
| Entrez Gene | 5127 |
|---|
Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human small intestine tissue showing apical membrane and cytoplasmic staining of glandular cells and cytoplasmic staining of interstitial cells.
Application
Western blot analysis of PCTAIRE-1 expression in non-transfected: (A) and mouse PCTAIRE-1 transfected: (B) 293T whole cell lysates.
Application
Western blot analysis of PCTAIRE-1 expression in non-transfected: (A) and mouse PCTAIRE-1 transfected: (B) 293T whole cell lysates.
Application
Western blot analysis of PCTAIRE-1 expression in U-87 MG (A), A549 (B) and MCF7 (C) whole cell lysates.| Application Notes | recommended for detection of PCTAIRE-1 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
