Application
Western blot analysis of CASZ1 expression in MCF7 nuclear extract.Application
Western blot analysis of CASZ1 expression in SKBR-3 whole cell lysate.| Product Name | CASZ1 Antibody (E-14) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an internal region of CASZ1 of human origin |
| Modification Notes | CASZ1 (castor zinc finger 1), also known as CST, SRG or ZNF693, is a 1,759 amino acid protein that localizes to the nucleus and contains eight C2H2-type zinc fingers. Expressed in stomach, lung, testis, pancreas, heart, skeletal muscle and small intestine, CASZ1 exists as multiple alternatively spliced isoforms and is thought to function as a transcription factor. Human CASZ1 shares over 85% sequence homology with its mouse counterpart, suggesting a conserved role between species. The gene encoding CASZ1 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of CASZ1 isoforms 1 and 2 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of CASZ1 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of CASZ1 of human origin |
| Entrez Gene | 54897 |
|---|
Application
Western blot analysis of CASZ1 expression in MCF7 nuclear extract.
Application
Western blot analysis of CASZ1 expression in SKBR-3 whole cell lysate.| Application Notes | recommended for detection of CASZ1 isoforms 1 and 2 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
