epitope mapping within an internal region of CBX6 of human origin
Modification Notes
Polycomb group (PcG) proteins form multiprotein complexes that regulate expression patterns of developmental and cell proliferation genes. CBX6 (chromobox protein homolog 6) is a 412 amino acid protein that is a component of the chromatin-associated PcG complex. Through interaction with PcG, CBX6 modifies chromatin and maintains the transcriptionally repressive state of genes. Members of the chromobox domain protein family are characterized by the presence of a 37 amino acid chromobox (CHRromatin Organization MOdifier) domain. This domain plays a mechanistic role in targeting chromodomain proteins to specific regions of the nucleus.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of CBX6 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine and bovine:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope mapping within an internal region of CBX6 of human origin
Tissue Specificity
epitope mapping within an internal region of CBX6 of human origin
Western blot analysis of CBX6 expression in Jurkat (A), NIH/3T3 (B) and 3611-RF (C) nuclear extracts.
Application
Western blot analysis of CBX6 expression in HeLa whole cell lysate.
Application Notes
recommended for detection of CBX6 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine and bovine:
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.