| Product Name | Chemokine Receptor D6 Antibody (M-66) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 313-378 mapping at the C-terminus of Chemokine Receptor D6 of mouse origin |
| Modification Notes | Chemokine Receptor D6 (also designated Chemokine-binding protein 2, C-C chemokine receptor D6, CCR-9, CCR-10, and CMKBR9) is a member of the C-C (b chemokine) G protein-coupled receptor family. This family is characterized by a pair of adjacent cysteine residues. C-C chemokine receptor family members also include CKR-1, CKR-2A, CKR-2B, CKR-3, CKR-4, CKR-5, CKR-6, CKR-7, CKR-8, CKR-9, CKR-10, CCXCKR, Bonzo, BOB (brother of Bonzo) and Duffy blood group antigen. Each of these receptors are G protein-coupled, seven pass transmembrane domain proteins whose major physiological role is to function in the chemotaxis of T cells and phagocytic cells to sites of inflammation. Chemokine Receptor D6 acts as a receptor for various C-C type chemokines, including SCYA2/MCP-1, SCY3/MIP-1-alpha, SCYA5/RANTES and SCYA7/MCP-3. It is expressed primarily in placental tissues and fetal liver, but is also detected in lymphatic endothelial cells, lymph nodes and mucosa of the small and large intestines. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Chemokine Receptor D6 of mouse, rat and, to a lesser extent, human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 313-378 mapping at the C-terminus of Chemokine Receptor D6 of mouse origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 313-378 mapping at the C-terminus of Chemokine Receptor D6 of mouse origin |
| Entrez Gene | 1238 |
|---|
| Application Notes | recommended for detection of Chemokine Receptor D6 of mouse, rat and, to a lesser extent, human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
