| Product Name | mPRγ Antibody (H-70) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 261-330 mapping at the C-terminus of mPRγ of human origin |
| Modification Notes | The steroid progesterone induces the resumption of maturation in oocytes via a nongenomic pathway through binding to a novel, membrane progestin receptor (mPR). This pathway inhibits adenylyl cyclase and reduces intracellular cAMP, and also activates mitogen-activated protein kinase to effect signal transduction pathways. Five distinct groups, designated alpha, beta, gamma, delta and epsilon, comprise this gene family, and while all contain 7 transmembrane domains, they show distinct distributions in reproductive, neural, kidney and intestinal tissues, respectively. These characteristics separate them from nuclear progestin receptors, and instead imply similarity to G-protein coupled receptors. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of mPRγ of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, bovine, porcine and canine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 261-330 mapping at the C-terminus of mPR&gamma of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 261-330 mapping at the C-terminus of mPRγ of human origin |
| Entrez Gene | 54852 |
|---|
| Application Notes | recommended for detection of mPRγ of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, bovine, porcine and canine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
