| Product Name | USP6/32 Antibody (H-300) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1117-1406 mapping at the C-terminus of USP6 of human origin |
| Modification Notes | Ubiquitin-specific protease (USP6) is a 1,406 amino acid protein that is very hydrophilic and has two charge clusters that are characteristic of nucleic acid-binding regions. The USP6 gene is oncogenic and originated from the chimeric fusion of two genes: USP32 and TBC1D3. USP32 is an ancient, highly conserved gene, whereas the TBC1D3 gene came from a relatively recent segmental duplication. This duplication is absent in most other mammals and shows rapid amplification and propagation throughout the primate lineage. The chimeric USP6, however, only exists in the hominoid lineage of primates, so it may have contributed to hominoid speciation. USP6 is testis-specific, suggesting an implication in the emergence of reproductive barriers. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of USP6 isoforms 1 and 2 of human origin and USP32 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1117-1406 mapping at the C-terminus of USP6 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1117-1406 mapping at the C-terminus of USP6 of human origin |
| Application Notes | recommended for detection of USP6 isoforms 1 and 2 of human origin and USP32 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
