| Product Name | PRODH Antibody (H-300) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 13-312 mapping near the N-terminus of PRODH of human origin |
| Modification Notes | PRODH (proline dehydrogenase), also known as proline oxidase 2 (POX2), is a 516 amino acid protein belonging to the proline oxidase family. Induced during p53-induced apoptosis, PRODH catalyzes the first step in proline degradation by converting proline to delta-1-pyrroline-5-carboxylate. Defects in PRODH are the cause of hyperprolinemia type 1, a disorder characterized by elevated serum proline levels. Defects in PRODH may also be involved in the psychiatric and behavioral phenotypes associated with DiGeorge syndrome. Localized to the mitochondrion matrix, PRODH is expressed at higher levels in lung, brain and skeletal muscle and expressed at lower levels in heart, liver, kidney and pancreas. PRODH exists as two isoforms produced by alternative splicing. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of PRODH of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 13-312 mapping near the N-terminus of PRODH of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 13-312 mapping near the N-terminus of PRODH of human origin |
| Entrez Gene | 5625 |
|---|
| Application Notes | recommended for detection of PRODH of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
