Application
Western blot analysis of LHFP expression in mouse heart tissue extract.| Product Name | LHFP Antibody (C-12) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping at the C-terminus of LHFP of human origin |
| Modification Notes | The development of lipomas, benign tumors composed of fatty tissues, have been linked to breakpoints in the HMGI-C gene. LHFP (lipoma HMGIC fusion partner) is a 200 amino acid multi-pass membrane protein that acts as a fusion partner with HMGI-C in a lipoma with the translocation t(12;13)(q13-q15;q12). Located on chromosome 13, the gene encoding LHFP is in a region that is frequently targeted by chromosomal aberrations in lipomas. The LHFP/HMGIC fusion transcript expresses 69 amino acids encoded by frame-shift LHFP sequences and three DNA binding domains of HMGIC. The mouse homolog of LHFP shares 94% sequence similarity with the human protein. With the exception of peripheral blood leukocytes, LHFP is ubiquitously expressed. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of LHFP of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine, porcine and avian: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping at the C-terminus of LHFP of human origin |
|---|---|
| Tissue Specificity | epitope mapping at the C-terminus of LHFP of human origin |
| Entrez Gene | 10186 |
|---|
Application
Western blot analysis of LHFP expression in mouse heart tissue extract.| Application Notes | recommended for detection of LHFP of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine, porcine and avian: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
