| Product Name | DSCR 1 Antibody (FL-197) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-197 representing full length DSCR 1 of human origin |
| Modification Notes | DSCR1 (Down Syndrome Critical Region 1) protein influences cardiac and nervous system development (1). DSCR1 is abundant in the brain, heart, and skeletal muscle. Overexpression of DSCR1 may play a role in the pathogenesis of Down syndrome, in particular mental retardation and/or cardiac defects. DSCR1 inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Human DSCR1 maps to gene locus 21q22.1-q22.2. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of DSCR 1 of mouse, rat and human origin by WB, IP, IF and ELISA may cross-react with RCAN2 or Calcipressin-3 also reactive with additional species, including canine and avian: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-197 representing full length DSCR 1 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-197 representing full length DSCR 1 of human origin |
| Entrez Gene | 1827 |
|---|
| Application Notes | recommended for detection of DSCR 1 of mouse, rat and human origin by WB, IP, IF and ELISA may cross-react with RCAN2 or Calcipressin-3 also reactive with additional species, including canine and avian: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
