| Product Name | NFKBIL1 Antibody (H-225) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 157-381 mapping at the C-terminus of NFKBIL1 of human origin |
| Modification Notes | NF˚B, a pleiotropic transcription factor, is present in almost all cell types and is involved in many biological processes including inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF˚B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. This complex is controlled by various mechanisms of post-translational modification and subcellular compartmentalization as well as by interactions with other cofactors or corepressors. The NF˚B inhibitor-like protein 1 (NFKBIL1), also designated IKBL, acts as a negative regulator of NF˚B activation. Mutations in the NFKBIL1 gene have been linked to several disorders including type 1 diabetes, rheumatoid arthritis, ulcerative colitis and chronic Chagas cardiomyopathy. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of NFKBIL1 of mouse, rat and human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 157-381 mapping at the C-terminus of NFKBIL1 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 157-381 mapping at the C-terminus of NFKBIL1 of human origin |
| Entrez Gene | 4795 |
|---|
| Application Notes | recommended for detection of NFKBIL1 of mouse, rat and human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
