Application
Western blot analysis of ALDH6A1 expression in mouse liver tissue extract.| Product Name | ALDH6A1 Antibody (H-178) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 181-358 mapping within an internal region of ALDH6A1 of human origin |
| Modification Notes | Aldehyde dehydrogenases (ALDHs) mediate the NADP+-dependent oxidation of aldehydes into acids and play an important role in the detoxification of alcohol-derived acetaldehyde, as well as in lipid peroxidation and in the metabolism of corticosteroids, biogenic amines and neurotransmitters. ALDH6A1 (aldehyde dehydrogenase family 6 member A1), also known as MMSDH or MMSADHA, is a 535 amino acid mitochondrial protein that belongs to the aldehyde dehydrogenase family. Considered a mitochondrial methylmalonate semialdehyde dehydrogenase, ALDH6A1 catalyzes the irreversible oxidative decarboxylation of malonate and methylmalonate semialdehydes to acetyl- and propionyl-CoA. It is suggested that ALDH6A1 plays a role in the valine and pyrimidine catabolic pathways. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of ALDH6A1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 181-358 mapping within an internal region of ALDH6A1 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 181-358 mapping within an internal region of ALDH6A1 of human origin |
| Entrez Gene | 4329 |
|---|
Application
Western blot analysis of ALDH6A1 expression in mouse liver tissue extract.| Application Notes | recommended for detection of ALDH6A1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
