| Modification Notes |
G-protein-coupled receptors (GPCRs) are receptors for most hormones and neurotransmitters and therefore play a large role in mediating cellular events. The class III GPCR family are metabotropic receptors for glutamate, gamma-aminobutyric acid (GABA), calcium, pheromones and certain gustatory stimulants. VN2R1P (Vomeronasal type-2 receptor-like), also known as putative calcium-sensing receptor-like 1) is a 755 amino acid multi-pass membrane protein that belongs to the GCPR class III family. VN2R1P possibly plays a role in olfactory sensation, due to the fact that other members of the C family of GCPRs function in this way. By receiving chemosensory information from a wide spectrum of pheromonal and odorant cues, VN2 proteins may influence critical animal behavior such as reproduction, feeding and social interactions. |