| Product Name | Cacna2d1 Antibody (H-147) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 25-171 mapping near the N-terminus of Cacna2d1 of human origin |
| Modification Notes | Voltage-dependent calcium channels are essential for the release of neurotransmitters. Cacna2d1 (calcium channel, voltage-dependent, alpha 2/delta subunit 1), also known as CACNA2, CCHL2A, MHS3 or CACNL2A, is a 1,091 amino acid single-pass type I membrane protein that contains one VWFA domain and one cache domain. Expressed in skeletal muscle, aorta tissues and in the central nervous system (CNS), Cacna2d1 functions as an alpha-2/delta subunit of voltage-dependent calcium channels and plays an important role in calcium current density, as well as in excitation-contraction coupling. The Cacna2d1 precursor is proteolytically processed to produce two functional subunits, designated alpha-2-1 and delta-1, which are disulfide-linked to one another. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Cacna2d1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 25-171 mapping near the N-terminus of Cacna2d1 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 25-171 mapping near the N-terminus of Cacna2d1 of human origin |
| Entrez Gene | 781 |
|---|
| Application Notes | recommended for detection of Cacna2d1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
