Application
Western blot analysis of SECp43 expression in non-transfected: (A) and mouse SECp43 transfected: (B) 293T whole cell lysates.| Product Name | SECp43 Antibody (H-120) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 141-260 mapping near the C-terminus of SECp43 of human origin |
| Modification Notes | SECp43, also known as tRNA (Sec) selenocysteine 1-associated protein 1 or TRNAU1AP, is a 287 amino acid member of the RRM TRSPAP protein family. Localized to the nucleus and cytoplasm, yet found more abundantly in the nucleus, SECp43 contains two RRM (RNA recognition motif) domains. The RRM domain contains two highly conserved regions: a six amino acid, hydrophobic motif (RNP-2) and an octapeptide motif (RNP-1). SECp43 is involved in the early stages of selenocysteine biosynthesis and tRNA charging. It is also involved in the later stages of the cotranslational incorporation of selenocysteine into selenoproteins. Possibly involved in the methylation of tRNA, SECp43 associates with mRNP, SELB, SBP-2 and tRNA. Two isoforms of SECp43 exist as a result of alternative splicing events. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of SECp43 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 141-260 mapping near the C-terminus of SECp43 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 141-260 mapping near the C-terminus of SECp43 of human origin |
| Entrez Gene | 54952 |
|---|
Application
Western blot analysis of SECp43 expression in non-transfected: (A) and mouse SECp43 transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of SECp43 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
